Cassava ( Manihot esculenta Crantz ) is a vital crop for millions, serving as a staple food and a key resource for industries ranging from starch production to bioethanol. Known for its adaptability to poor soils and unpredictable rainfall, cassava has earned its place as a "future crop" in the face of climate change. However, its sensitivity to cold stress has limited its potential in temperate regions, leaving a gap in understanding how this resilient plant can thrive in colder climates. This book brings together the latest research on cassava's response to cold stress, exploring its physiological, genetic, and metabolic mechanisms. Drawing on insights from agronomy and biotechnology, it examines the possibilities of developing cold-tolerant cultivars using the genetic diversity found in international germplasm banks. The authors also discuss practical strategies to scale up cassava production in new regions, offering hope for expanded cultivation and industrial use. Ideal for researchers, plant breeders, and policymakers, Underlying Mechanisms of Cassava Cold Tolerance highlights the untapped potential of this crop. By addressing one of its greatest challenges, this book opens the door to a more sustainable and food-secure future.