This book explores ways in which systems of local knowledge, culture, language, and place are foundational for STEM learning in Indigenous communities. It is part of a two-volume set that addresses a growing recognition that interdisciplinary, cross-cultural and cross-hybrid learning is needed to foster scientific and cultural understandings and move STEM learning toward more just and sustainable futures for all learners.  Themes of learning from elders, through practice and place-based experiences are found across cultures. Each chapter brings a uniquely Indigenous point of view to the educational transformation efforts taking place in these distinct contexts.  In the second section the chapters use authentic research stories to explain many ways in which regular disciplinary policies and practices can impact Indigenous students' participation in STEM classrooms and careers. These authors go on to discuss ways to engage learners in STEM activities that are interconnected with the contexts of their lives.