This book constitutes the refereed proceedings of the First international conference on Global Mental Health and Public Health Challenges and Innovation, held in Ranchi, Jharkhand, India, in November 25-27, 2022. The 7 full papers in this book were carefully reviewed and selected from 62 submissions. These papers focus on the Application of modern techniques, such as Internet of Things (IoT), Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL), to the current challenges in the field of Mental health and public health.