This book analyzes the role of institutions in conditioning entrepreneurship and innovation to achieve economic development. Set against the backdrop of populism, this book is based on the premise that formal and informal institutional factors and entrepreneurship are closely linked and that studying the economic development of both developed and emerging economies can help us disentangle the role of entrepreneurship and innovation in developing countries. Using institutional economics as a main theoretical framework and the sociotechnical subsystems as a complementary approach, the authors present a detailed literature review to demonstrate that it is possible to identify the true role of entrepreneurship and innovation in the economic development process. The book embraces complexity to better measure and comprehend economic development, bringing a more compelling perspective on the importance of entrepreneurship and innovation for different dimensions ofdevelopment. A valuable resource for students, scholars, and policymakers, the authors offer clear recommendations for developing countries.