In this issue of Veterinary Clinics: Exotic Animal Practice, guest editors Drs. Dario d'Ovidio and Domenico Santoro bring their considerable expertise to the topic of Dermatology. Infectious and non-infectious dermatological diseases are very common in exotic animals and are one of the most frequently seen presenting complaints in exotic animal practice. In this issue, top experts discuss common infectious and non-infectious conditions, recent diagnostic tests, new drugs and therapies, and dermatoses with zoonotic potential as well as the measures to prevent their transmission to cohabitant human beings.