This volume is devoted to the natural philosopher Bernardino Telesio (1509-1588) and his place in the scientific debates of the Renaissance. Telesio’s thought is emblematic of Renaissance culture in its aspiration towards universality; the volume deals with the roots and reception of his vistas from an interdisciplinary perspective ranging from the history of philosophy to that of physics, astronomy, meteorology, medicine, and psychology. The editor, Pietro Daniel Omodeo and leading specialists of intellectual history introduce Telesio’s conceptions to English-speaking historians of science through a series of studies, which aim to foster our understanding of a crucial early modern author, his world, achievement, networks, and influence. Contributors are Roberto Bondì, Arianna Borrelli, Rodolfo Garau, Giulia Giannini, Miguel Ángel Granada, Hiro Hirai, Martin Mulsow, Elio Nenci, Pietro Daniel Omodeo, Nuccio Ordine, Alessandro Ottaviani, Jürgen Renn, Riccarda Suitner, and Oreste Trabucco.