This book constitutes the thoroughly refereed proceedings of five international workshops held in Ljubljana, Slovenia, in conjunction with the 28th International Conference on Advanced Information Systems Engineering, CAiSE 2016, in June 2016. The 16 full and 9 short papers were carefully selected from 51 submissions. The associated workshops were the Third International Workshop on Advances in Services DEsign based on the Notion of CApabiliy (ASDENCA) co-arranged with  the First International Workshop on Business Model Dynamics and Information Systems Engineering (BumDISE), the Fourth International Workshop on Cognitive Aspects of Information Systems Engineering (COGNISE), the First International Workshop on Energy-awareness and Big Data Management in Information Systems (EnBIS), the Second International Workshop on Enterprise Modeling (EM), and the Sixth International Workshop on Information Systems Security Engineering (WISSE).